Experimental–Numerical Characterization of Cold Atmospheric Pressure Plasma Jet for Biomedical Applications Using Moiré Deflectometry
DOI:
https://doi.org/10.63053/ijhes.186Keywords:
Cold atmospheric plasma, Moiré deflectometry, Biomedical application, Electron density, Refractive indexAbstract
Cold atmospheric pressure plasma jets (CAPJs) have attracted considerable attention for biomedical applications due to their non-thermal behavior and their ability to generate a high density of reactive species. In this study, an integrated experimental–numerical approach is employed to characterize the propagation dynamics and refractive-index variations induced by a CAPJ using Moiré deflectometry. This optical technique, based on wavefront analysis and geometric optics, enables precise detection of refractive-index gradients generated in the jet–ambient interface. As the plasma jet interacts with the surrounding environment, the resulting changes in optical path manifest as fringe deflections, which are recorded using a CCD camera. By applying improved digital image-processing algorithms developed in MATLAB, the refractive-index field and associated plasma parameters are quantitatively reconstructed with high accuracy. The results demonstrate that Moiré deflectometry is a powerful, non-intrusive diagnostic tool for resolving small refractive-index variations and understanding CAPJ behavior, providing valuable insights for optimizing plasma sources in biomedical applications
References
[1] Khanzadeh, Mohammad, Fatemeh Jamal, and Mahdi Shariat. "Experimental investigation of gas flow rate and electric field effect on refractive index and electron density distribution of cold atmospheric pressure-plasma by optical method, Moiré deflectometry." Physics of Plasmas 25, no. 4 (2018): 043516.
[2] R. W. Boyd,” Nonlinear optics, Handbook of Laser Technology and Applications”. (2003). 161-183.
[3] Lin, Su-Shia. "Optical properties of TiO2 nanoceramic films as a function of N–Al co-doping." Ceramics International 35.7 (2009): 2693-2698.
[4] Kazemi, A., Nicol, M. J., Bilén, S. G., Kirimanjeswara, G. S., & Knecht, S. D. (2024). Cold Atmospheric Plasma Medicine: Applications, Challenges, and Opportunities for Predictive Control. Plasma, 7(1), 233–257. DOI:10.3390/plasma7010014
[5] Tan, F., Wang, Y., Zhang, S., Shui, R., & Chen, J. (2022). Plasma Dermatology: Skin Therapy Using Cold Atmospheric Plasma. Frontiers in Oncology, 12, 918484. DOI:10.3389/fonc.2022.918484
[6] Farahani, S. S., & Madanipour, K. (2017, June). Nonlinear absorption coefficient measurement of nanofluids using Moire deflectometry technique. In Optical Methods for Inspection, Characterization, and Imaging of Biomaterials III (Vol. 10333, p. 103331I). International Society for Optics and Photonics.
[7]Frontiers in Medicine (2025). Mechanisms of cold atmospheric plasma action in chronic wound healing: Effects on inflammation, angiogenesis, and tissue remodeling. Frontiers in Medicine, 12, 1527736. DOI:10.3389/fmed.2025.1527736
[8] Irimpan, L., Nampoori, V. P. N., Radhakrishnan, P., Krishnan, B., & Deepthy, A. (2008). Size-dependent enhancement of nonlinear optical properties in nanocolloids of ZnO. Journal of applied physics, 103(3), 033105.
[9] Ara, M. M., Mousavi, S. H., Salmani, S., & Koushki, E. (2008). Measurement of nonlinear refraction of dyes doped liquid crystal using moiré deflectometry. Journal of Molecular Liquids, 140(1-3), 21-24
[10] Y. Song, Y. Y. Chen, A. He, and Z. Zhao, “Theoretical analysis for moir_e deflectometry from diffraction theory,” JOSA A 26(4), 882–889 (2009).
[11] Bernhardt, T., et al. (2019). Plasma Medicine: Applications of Cold Atmospheric Pressure Plasma in Dermatology. Journal of Investigative Dermatology, 139(7), 1509–1518. DOI: 10.1016/j.jid.2019.02.004
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Authors

This work is licensed under a Creative Commons Attribution 4.0 International License.
Articles published in the International Journal of New Findings in Health and Educational Sciences (IJHES) are licensed under the Creative Commons Attribution 4.0 International License (CC BY 4.0).
You are free to:
-
Share — Copy and redistribute the material in any medium or format for any purpose, including commercially.
-
Adapt — Remix, transform, and build upon the material for any purpose, including commercially.
-
No Revocation — The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
-
Attribution — You must give appropriate credit to the original author(s) and the original publication, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in a way that suggests the author(s), IJHES, or the publisher endorses you or your use.
-
No Additional Restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Authors retain copyright in their work. By publishing with IJHES, authors grant the journal and Arvin Arena Scientific Publication the necessary non-exclusive rights to publish, reproduce, distribute, archive, and make the article publicly available.
Recommended attribution:
Author(s), “Article Title,” International Journal of New Findings in Health and Educational Sciences (IJHES), Year, DOI. Licensed under CC BY 4.0.
For the complete license terms, please refer to the Creative Commons Attribution 4.0 International License (CC BY 4.0).



