Effectiveness of Acceptance and Commitment Therapy on Resilience, Self-Deprecation, and Self-Help in People with Chronic Depressive Disorder with Frequent Relapses
DOI:
https://doi.org/10.63053/ijhes.204Keywords:
Acceptance and Commitment Therapy, Chronic Depression, Resilience, Self-Deprecation, Self-Help, Frequent RelapseAbstract
Background: Chronic Major Depressive Disorder (MDD) with frequent relapses is a debilitating condition characterized by low resilience, high self-deprecation, and impaired self-help behaviors. Acceptance and Commitment Therapy (ACT), which targets psychological inflexibility, may address these specific deficits. This study aimed to investigate the effectiveness of ACT on resilience, self-deprecation, and self-help in individuals with chronic MDD with frequent relapses.
Methods: This quasi-experimental study employed a pretest-posttest-follow-up design with a control group. The statistical population included all patients aged 25–55 years with chronic MDD and a history of at least three depressive episodes attending psychiatric clinics in Tehran during 2024–2025. A total of 45 participants were selected using purposive sampling and randomly assigned to ACT (n = 15) and waitlist control (n = 15) groups, with 15 participants in each group completing the study. The ACT group received ten 90-minute weekly group sessions. Data collection instruments included the Beck Depression Inventory-II (BDI-II), Connor-Davidson Resilience Scale (CD-RISC), Self-Deprecation Scale (SDS), and Self-Help Behaviors Scale (SHBS). Data were analyzed using repeated-measures ANOVA with SPSS-26.
Results: The ACT group demonstrated significant improvements compared to the control group across all outcome measures. Significant Time × Group interactions were found for resilience (F = 28.45, P < 0.001, η² = 0.48), self-deprecation (F = 32.18, P < 0.001, η² = 0.52), and self-help behaviors (F = 26.73, P < 0.001, η² = 0.46). Improvements were maintained at two-month follow-up (P < 0.001). Effect sizes for ACT were large (d = 2.12 for resilience; d = 2.34 for self-deprecation; d = 1.98 for self-help). Depression severity significantly decreased in the ACT group (F = 35.28, P < 0.001, η² = 0.56).
Conclusion: Acceptance and Commitment Therapy is an effective intervention for improving resilience, reducing self-deprecation, and enhancing self-help behaviors in individuals with chronic depressive disorder with frequent relapses. The therapeutic benefits are sustained over time and are associated with reduced depression severity. ACT should be considered a frontline psychological treatment for chronic, relapsing depression.
References
1. Abdoli N, Salari N, Darvishi N, Jafarpour S, Solaymani M, Mohammadi M, Shohaimi S. The global prevalence of major depressive disorder (MDD) among the elderly: A systematic review and meta-analysis. Neurosci Biobehav Rev. 2022;132:1067-73.
2. Hasin DS, Sarvet AL, Meyers JL, Saha TD, Ruan WJ, Stohl M, Grant BF. Epidemiology of adult DSM-5 major depressive disorder and its specifiers in the United States. JAMA Psychiatry. 2018;75(4):336-46.
3. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Arlington (VA): American Psychiatric Publishing; 2013.
4. Connor KM, Davidson JR. Development of a new resilience scale: The Connor-Davidson Resilience Scale (CD-RISC). Depress Anxiety. 2003;18(2):76-82.
5. Garrivet J, Gohier B, Laviole G, Meslier N, Gagnadoux F, Trzepizur W. Prevalence of major depressive disorder and post-traumatic stress disorder among first-time sleep center attendees. Sleep Med. 2024;119:53-7.
6. Southwick SM, Charney DS. The science of resilience: Implications for the prevention and treatment of depression. Science. 2012;338(6103):79-82.
7. Wright SR, Graham CD, Houghton R, Ghiglieri C, Berry E. Acceptance and commitment therapy (ACT) for caregivers of children with chronic conditions: A mixed methods systematic review (MMSR) of efficacy, process, and acceptance. J Contextual Behav Sci. 2023;27:72-97.
8. Beck AT. Cognitive therapy of depression. New York: Guilford Press; 1979.
9. Gilbert P. The compassionate mind. London: Robinson; 2009.
10. Neff KD. Self-compassion: An alternative conceptualization of a healthy attitude toward oneself. Self Identity. 2003;2(2):85-101.
11. MacBeth A, Gumley A. Exploring compassion: A meta-analysis of the association between self-compassion and psychopathology. Clin Psychol Rev. 2012;32(6):545-52.
12. Schwarzer R, Jerusalem M. Generalized self-efficacy scale. In: Weinman J, Wright S, Johnston M, editors. Measures in health psychology: A user's portfolio. Windsor: NFER-Nelson; 1995. p. 35-7.
13. Bandura A. Self-efficacy: The exercise of control. New York: Freeman; 1997.
14. Simon GE, VonKorff M, Barlow W, Pabiniak C, Wagner E, Katon W. Predictors of chronicity in primary care patients with anxiety disorders. Arch Gen Psychiatry. 1996;53(10):895-9.
15. Bai Z, Luo S, Zhang L, Wu S, Chi I. Acceptance and commitment therapy (ACT) to reduce depression: A systematic review and meta-analysis. J Affect Disord. 2020;260:728-37.
16. Hayes SC, Strosahl KD, Wilson KG. Acceptance and commitment therapy: The process and practice of mindful change. 2nd ed. New York: Guilford Press; 2012.
17. Hayes SC, Luoma JB, Bond FW, Masuda A, Lillis J. Acceptance and commitment therapy: Model, processes and outcomes. Behav Res Ther. 2006;44(1):1-25.
18. Twohig MP, Levin ME. Acceptance and commitment therapy as a treatment for anxiety and depression: A review. Psychiatr Clin North Am. 2017;40(4):751-70.
19. Bayat M, Beshrpour S, Aghajani S, Mikaili N. Comparing the effectiveness of emotional schema therapy and acceptance and commitment therapy on the severity of depressive symptoms and distress tolerance in people with major depressive disorder. Rooyesh. 2025;14(6):41-52.
20. Tarkhan M. The effectiveness of acceptance and commitment therapy (ACT) on emotion regulation and life meaning of depressed women. J Psychol Stud. 2017;13(3):147-64.
21. Mosapor M. The effectiveness of acceptance and commitment therapy on distress tolerance, rumination and experiential avoidance in adolescents with depression. Sci J Soc Psychol. 2023;11(67):77-92.
22. Dehghan H, Najarpour Ostadi S, Mojtabaei M. The effectiveness of acceptance and commitment-based therapy on emotional instability and self-injurious behaviors of people with borderline personality disorder and drug abusers. Rooyesh. 2023;12(10):89-98.
23. Ruiz FJ. A review of Acceptance and Commitment Therapy (ACT) empirical evidence: Correlational, experimental psychopathology, component and outcome studies. Int J Psychol Psychol Ther. 2010;10(1):125-62.
24. Gloster AT, Walder N, Levin ME, Twohig MP, Karekla M. The empirical status of acceptance and commitment therapy: A meta-analysis of component and process studies. J Contextual Behav Sci. 2024;32:100756.
25. Haller H, Breilmann P, Schröter M, Dobos G, Cramer H. A systematic review and meta-analysis of acceptance- and mindfulness-based interventions for DSM-5 anxiety disorders. Front Psychol. 2021;12:713-28.
26. Ghaderi A, Neshat Doost HT, Abedi MR, Kalantari M. An overview of reviews on the effects of acceptance and commitment therapy on depression and anxiety. Iran J Psychiatry. 2023;18(2):248-57.
27. Dabson KS, Mohammadkhani P, Fata L, et al. Validation of the Beck Depression Inventory-II in Iranian adolescents. Iran J Psychiatry Clin Psychol. 2007;13(3):266-73.
28. Mohammadi MR, Salmanian M, Khaleghi A. Psychometric properties of the Connor-Davidson Resilience Scale in Iranian clinical sample. Iran J Psychiatry. 2019;14(4):289-97.
29. Besharat MA, Pourbohlool S. Psychometric properties of the Self-Deprecation Scale in Iranian adults. J Clin Psychol. 2018;10(2):67-82.
30. Fallahi M. Psychometric properties of the Self-Help Behaviors Scale in Iranian chronic disease patients. J Health Promot Manag. 2015;4(3):45-54.
31. Rezaee M, Ghazanfari F, Rezaee F. Effectiveness of emotional schema therapy on severity of depression and rumination in people with major depressive disorder. J Shahid Sadoughi Univ Med Sci. 2016;24(1):41-54.
32. Ghasemkhanloo A, Atadokht A, Sabri V. The effectiveness of emotional schema therapy on severity of depression and cognitive emotional regulation strategies in major depression disorder. J North Khorasan Univ Med Sci. 2022;14(1):38-44.
33. Li Y, Ju R, Hofmann SG, Chiu W, Guan Y, Leng Y, Liu X. Distress tolerance as a mechanism of mindfulness for depression and anxiety: Cross-sectional and diary evidence. Int J Clin Health Psychol. 2023;23(4):1003-92.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Authors

This work is licensed under a Creative Commons Attribution 4.0 International License.
The journal is licensed under a Attribution 4.0 International (CC BY 4.0).
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution - You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions - You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.



