Examining clinical evidence of the impact of anti-inflammatory interventions on mental health and sexual performance

Omid Malekpour; Amir Mahdi Malekpour

doi:10.63053/ijhes.160

Authors

Omid Malekpour 1. Master's degree graduate in Clinical Psychology, Faculty of Psychology and Educational Sciences, Shahid Beheshti University, Tehran, Iran
Amir Mahdi Malekpour 2. Doctoral student in professional medicine, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran

DOI:

https://doi.org/10.63053/ijhes.160

Keywords:

Mental Health, Sexual Performance, Anti-Inflammatory Interventions, Systemic Inflammation

Abstract

Compelling evidence indicates that chronic inflammation plays a key role in the pathophysiology of mental disorders and sexual dysfunction. This article examines the effects of anti-inflammatory methods on improving mental health and sexual performance. The reviews suggest that various interventions targeting inflammatory pathways and reducing pro-inflammatory factors may lead to significant improvements. In mental health, omega-3 supplements, turmeric, and vitamin D can exhibit antidepressant and anxiolytic effects, especially in individuals with high baseline inflammation or treatment resistance. Adjunct medications such as minocycline and anti-inflammatory inhibitors have also shown positive results, but side effects are a concern. In sexual performance, improvements are primarily seen in erectile function, achieved through enhanced vascular health, increased nitric oxide, and reduced inflammation. The Mediterranean diet and regular physical activity are the safest and most effective interventions that enhance mental health and sexual performance by reducing inflammation, improving metabolic health, and regulating stress responses. Despite promising results, the heterogeneity of studies, the need to identify subgroups based on inflammatory indices, safety considerations, and drug interactions are important points in these interventions. Ultimately, anti-inflammatory interventions, particularly lifestyle changes and certain supplements, are promising strategies, but their broader implementation requires longer trials and more precise designs.

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