Electrochemical Measurement of Platinum Drug Using Carbon Paste Electrode Modified with Silver Nanoparticles and Modifier

Authors

  • Mohammad Reza Baezzat Department of Chemistry, Faculty of Basic Sciences, Payam Noor University, Tehran, Iran
  • Arash Sedighi Nasab Department of Chemistry, Faculty of Basic Sciences, Payam Noor University, Tehran, Iran
  • Sedigheh Kamran Department of Chemistry, Faculty of Basic Sciences, Payam Noor University, Tehran, Iran

DOI:

https://doi.org/10.63053/ijhes.85

Keywords:

Silver Nanoparticles, Platinum, Graphene,Modified Electrode

Abstract

This paper used a carbon paste electrode modified with graphene functionalized with silver nanoparticles and triphenylphosphine to measure the drug Platinol. Raman, Fourier Transform Infrared Spectroscopy (FTIR), and Scanning Electron Microscope (SEM) techniques were used to study the behaviour of Platinol. The electrochemical behavior of platinum on a carbon paste electrode modified with silver nanoparticles and 4-Hydroxy-2-(Triphenylphosphine) was analyzed. Differential Pulse Voltammetry (DPV) in the concentration range of 1-120 μM was linearized in two ranges of 1-20 μM and 20-120 μM, and the detection limit of 0.88 μM was obtained. The effects of disturbing on different species were studied to determine the selectivity. The platinum measurement method was used with the mentioned electrode in actual samples.

References

-Vinay Kumar, Abul K. Abbas, Nelson Fausto, Nelson Fausto. Robbins & Cotran Pathologic Basis of Disease. Chapter 7, 7th Ed.

-Kinzler KW, Vogelstein B (2002) Genetic Basis of Human Cancer. McGraw-Hill.

-Kurzrock R, Talpaz M (1999) Molecular Biology in Cancer Medicine. Pearson Education, Harlow.

-Lakshmi MS, Sherbet GV (1997) Genetics of Cancer: Genes Associated With Cancer Invasion, Metastasis and Cell Proliferation. Academic Press, London.

-McDonald F, Ford CHG (1997) Molecular Biology of Cancer. Springer-Verlag New York, Incorporated.

-Iran's generic drugs dictionary, Dr. Heshmati, 2007.

-Optimizing the synthesis method of the cisplatin anticancer drug, Roya Kiani Anbohi, Ahmad Sharifizadeh, Sakineh Meftah, National Conference on New Findings of Chemistry in Industry and Medicine, 2007.

Published

2024-07-01

How to Cite

Baezzat, M. R., Sedighi Nasab, A., & Kamran, S. (2024). Electrochemical Measurement of Platinum Drug Using Carbon Paste Electrode Modified with Silver Nanoparticles and Modifier . International Journal of New Findings in Health and Educational Sciences (IJHES), 2(3), 21–29. https://doi.org/10.63053/ijhes.85

Issue

Section

Articles